N+ Cyclone™ Neuro Micro-Guidewire Structural Design

Structural Configuration Overview

1. Distal End Architecture

• Platinum Coil Construction: High-density platinum windings provide exceptional fluoroscopic visibility while maintaining atraumatic flexibility for delicate neurovascular navigation.

• Custom-Shapeable Tip: Platinum coil tip can be manually shaped to match specific vessel anatomy, enabling precise directional control and selective catheterization.

2. Transition Zone Engineering

• Multi-Tapered Core Design: Gradually tapered stainless steel core creates a seamless transition from proximal stiffness to distal flexibility, optimizing pushability without compromising trackability.

• Hydrophilic Coating Segment: Distal 25 cm features uniform hydrophilic polymer coating (activated upon saline contact) that reduces surface friction by ≥70%, facilitating smooth passage through tortuous vasculature.

3. Proximal End System

• Hypotube Reinforcement: High-strength stainless steel hypotube provides exceptional column strength and torque response, ensuring 1:1 rotational control during complex navigation.

• Proximal Handle Design: Color-coded ergonomic handle with torque device compatibility allows for precise single-handed operation and immediate procedural recognition.

Technical Integration

Core-to-Coil Transition

• Laser-Welded Junction: Precision laser welding between tapered core and platinum coil creates a smooth, fracture-resistant transition zone

• Variable Pitch Coiling: Progressive coil winding density adjusts from proximal support to distal flexibility

• Tip Load Options: Available in 2g (soft) and 4g (medium) configurations for different clinical requirements

Coating Technology

• Dual-Layer Hydrophilic System:

• Base layer: Polyurethane bonding substrate

• Surface layer: Cross-linked hydrogel polymer

• Lubricity Performance: Coefficient of friction <0.05 when hydrated

• Durability: Maintains lubricity through >10 passes in simulated tortuous anatomy

Radiopaque Markers

• Primary Marker: Platinum coil tip (3mm length)

• Secondary Marker: Tantalum band at 3cm from tip

• Tertiary Marker: Additional band at 10cm for positioning reference

Performance Characteristics

Mechanical Properties

• Torque Transmission: 1:1 response within 180° rotation

• Tip Deflection Force: 0.5-2.0 mN depending on configuration

• Column Strength: 150 gf buckling resistance

• Fatigue Resistance: >100,000 cycles at 90° bend

Clinical Performance Metrics

• Trackability: Successfully navigates 180° turns with 2mm radius

• Crossing Profile: 0.014" (0.36mm) distal diameter

• Visualization: 3-point radiopaque system for precise localization

• Recoil Time: Returns to straight configuration within 0.5 seconds